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pubmed-article:12010881pubmed:abstractTextLeptin, a hormone mainly produced by fat cells, acts primarily on the hypothalamus regulating energy expenditure and food intake. Leptin receptors are expressed in several tissues and the possible physiological role of leptin is being extensively investigated, with the result that important peripheral actions of the hormone in the organism are being discovered. Recent studies have demonstrated leptin and leptin receptor expression in gastric epithelial cells. In the present study, we report the presence of the long leptin receptor isoform (OB-Rb) in human, rat, and mouse small intestine, supporting the hypothesis of leptin as a hormone involved in gastrointestinal function.lld:pubmed
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pubmed-article:12010881pubmed:articleTitleDistribution of the long leptin receptor isoform in brush border, basolateral membrane, and cytoplasm of enterocytes.lld:pubmed
pubmed-article:12010881pubmed:affiliationDepartment of Physiology and Nutrition, University of Navarra, Pamplona, Spain.lld:pubmed
pubmed-article:12010881pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:12010881pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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