Linked Life Data

12008709

Source:http://linkedlifedata.com/resource/pubmed/id/12008709

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2002-5-13
pubmed:abstractText
Reports on postflight examination of lymphocytes from crew members of soviet and american spaceships show a depression of reactivity towards mitogens in vitro. The purpose of this communication is to present experimental evidence that gravity can interfere with lymphocyte activation. Lymphocytes were incubated in the presence of concanavalin A in a centrifuge at 2 and 4 g for four days. This environment causes a significant acceleration of the response to the mitogen. In addition, remarkable differences in the ultrastructure of cells grown at 1 g and 4 g are observed by electron microscopy. This investigation is related to the experiment "Effect of weightlessness on lymphocyte proliferation" experiment which will be performed during the first Spacelab mission.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
S
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0075-9422
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NASA
pubmed:authorsComplete
Y
pubmed:pagination
219-24
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
Effect of gravity on lymphocyte proliferation.
pubmed:affiliation
Laboratorium fur Biochemie, Institut fur Zellbiologie, ETH-Zentrum, Zurich, Switzerland.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't