Linked Life Data

12004938

Source:http://linkedlifedata.com/resource/pubmed/id/12004938

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2002-5-13
pubmed:abstractText
A high-performance liquid chromatographic method for the determination and pharmacokinetic study of cinnamic acid in the plasma of rats after having been administrated orally with the traditional Chinese medicinal (TCM) preparation Ling-Gui-Zhu-Gan decoction is established. Plasma samples taken from rats are acidified with hydrochloric acid and extracted with ethyl acetate. Separation of the main effective constituent cinnamic acid is accomplished on a C18 stationary phase and a mobile phase of methanol-acetonitrile-2% glacial acetic acid (10:22:70, v/v) with a UV detector setting at 254 nm. After validation, the method is used to take a limited view of pharmacokinetic profiles of the TCM preparation of the Ling-Gui-Zhu-Gan decoction.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0021-9665
pubmed:author
pubmed:issnType
Print
pubmed:volume
40
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
198-200
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
An HPLC method for the determination and pharmacokinetic study of cinnamic acid in the plasma of rats having taken the traditional Chinese medicinal preparation Ling-Gui-Zhu-Gan decoction.
pubmed:affiliation
Shenyang Pharmaceutical University, Liaoning Province, PR China.
pubmed:publicationType
Journal Article