Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2002-4-16
pubmed:abstractText
The behavior of Vbeta2(+) T cells reactive with the pathogenic superantigen toxic shock syndrome toxin-1 (TSST-1) was examined in 12 patients with neonatal TSS-like exanthematous disease (NTED). In 8 patients, the percentage of Vbeta2(+) T cells in peripheral blood (PB) T cells had increased to three times the level in methicillin-resistant Staphylococcus aureus (MRSA)-free neonatal controls, when examined on days 4 to 7 of life. In the remaining 4 patients, however, the percentage of Vbeta2(+) T cells was significantly low, i.e., ranging from less than 10% to 30% of the control level, when they were examined on days 4 to 8 of life, and the percentage increased dramatically several days later, indicating that these patients actually had NTED. We recommend that, in patients who are suspected of having NTED, when an increase in Vbeta2(+) T cells is not observed in a comparatively early period of the illness, reassessment of the Vbeta2(+) T cells should be carried out 2 to 4 days later, to obtain a conclusive diagnosis of NTED.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1341-321X
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
111-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
The percentage of superantigen-reactive T cells in peripheral blood significantly decreases before massively increasing in patients with neonatal TSS-like exanthematous disease in the early acute phase.
pubmed:affiliation
Department of Microbiology and Immunology, Tokyo Women's Medical University School of Medicine, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan. tuchi@research.twmu.ac.jp
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't