Source:http://linkedlifedata.com/resource/pubmed/id/11950116
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
2002-4-12
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| pubmed:abstractText |
A retrospective study was conducted on 72 children admitted to a medical center in Taiwan due to invasive pneumococcal infections diagnosed between January 1990 and April 2000. Of these patients, 28 had meningitis and 44 had other invasive diseases. Forty-one (56.9%) strains of Streptococcus pneumoniae showed reduced susceptibility to penicillin by the oxacillin disc diffusion method. The total mortality was 20.8%, 32.1% for meningitis, and 13.6% for other invasive diseases. Ten (52.6%) of the patients survived from meningitis had long-term sequelae. Statistical analysis showed that initial presentation of coma, shock, respiratory distress requiring mechanical ventilation, and leukopenia (leukocyte <4,000 /mm3) were associated with mortality of invasive pneumococcal infections. Low cerebrospinal fluid leukocyte count (<50 /mm3) and high cerebrospinal fluid protein level (> or = 660 mg/dL) were also associated with mortality of meningitis. The presence of underlying diseases and high alanine aminotransferase level (> or = 100 U/L) were associated with fatal non-meningitic invasive diseases. Patients with shock and high alanine aminotransferase level but without high C-reactive protein level (> or = 20 mg/dL) were associated with rapidly fatal outcome. The outcome of invasive pneumococcal diseases was not associated with penicillin susceptibility.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Mar
|
| pubmed:issn |
1684-1182
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
35
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| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
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| pubmed:pagination |
23-8
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| pubmed:dateRevised |
2007-6-21
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| pubmed:meshHeading |
pubmed-meshheading:11950116-Adolescent,
pubmed-meshheading:11950116-Child,
pubmed-meshheading:11950116-Child, Preschool,
pubmed-meshheading:11950116-Drug Resistance, Bacterial,
pubmed-meshheading:11950116-Female,
pubmed-meshheading:11950116-Humans,
pubmed-meshheading:11950116-Infant,
pubmed-meshheading:11950116-Infant, Newborn,
pubmed-meshheading:11950116-Male,
pubmed-meshheading:11950116-Pneumococcal Infections,
pubmed-meshheading:11950116-Prognosis,
pubmed-meshheading:11950116-Retrospective Studies
|
| pubmed:year |
2002
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| pubmed:articleTitle |
Clinical outcome of invasive pneumococcal infection in children: a 10-year retrospective analysis.
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| pubmed:affiliation |
Department of Pediatrics, Taichung Veterans General Hospital, Taiwan, ROC.
|
| pubmed:publicationType |
Journal Article
|