Source:http://linkedlifedata.com/resource/pubmed/id/11943882
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2002-4-10
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pubmed:abstractText |
There is increasing evidence to suggest that 'cross-talk' occurs between G-protein-coupled receptors and their intracellular second messenger pathways. Cross-talk between different pathways may occur at the level of receptors, G-proteins, effectors or second messengers and may serve to fine-tune cell signalling. There is a growing body of evidence to suggest that cellular compartmentalization may play a crucial role in regulating these cross-talk interactions. Understanding the mechanisms of cross-talk may therefore be the key to the design and application of future therapeutics and the development of drug specificity.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1424-862X
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2002 S. Karger AG, Basel
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pubmed:issnType |
Print
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
45-57
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading | |
pubmed:articleTitle |
Mechanisms of cross-talk between G-protein-coupled receptors.
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pubmed:affiliation |
Institute of Cell Signalling and School of Biomedical Sciences, Queens Medical Centre, Nottingham, UK. yolande.cordeaux@nottingham.ac.uk
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pubmed:publicationType |
Journal Article,
Review
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