Linked Life Data

11871755

Source:http://linkedlifedata.com/resource/pubmed/id/11871755

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2002-3-1
pubmed:abstractText
Organic chemicals from the Polish maximum allowable concentration (MAC) list were analyzed for skin notation. It can be concluded that the dermal dose LD50s determined on experimental animals ought to be adopted as the fundamental criterion for providing a substance with the percutaneous absorption notation in the MAC list. All chemicals with LD50s. value below 1,000 mg/kg should be provided with the Sk index in the MAC list. For other chemicals, a skin notation would be considered when repeated human and dermal application tests have shown significant systemic effects following exposure. When information on the characteristics specified above were not available, physicochemical data required to calculate the flow (solubility, octanol/water partition coefficient, molecular weight) were obtained to consider a skin notation.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1047-322X
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
187-99
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Assignment of skin notation for maximum allowable concentration (MAC) list in Poland.
pubmed:affiliation
Nofer Institute of Occupational Medicine, Lód?, Poland.
pubmed:publicationType
Journal Article