Linked Life Data

11854538

Source:http://linkedlifedata.com/resource/pubmed/id/11854538

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
120
pubmed:dateCreated
2002-2-20
pubmed:abstractText
Infrared-guided laser stimulation is a new technique that allows precise and rapid stimulation of visualized neurons in brain slices. Infrared imaging of neurons with a new contrast system is combined with the photolytic release of caged neurotransmitters by an ultraviolet (UV) laser. Addition of caged neurotransmitters to the superfusion medium of neurons in brain slices allows local excitation in the micrometer range with a focused spot of UV light. In this way, the distribution of glutamate or gamma-aminobutyric acid (GABA) receptors on neuronal dendrites can be mapped. Furthermore, this technique can be used to map the connectivity of neuronal networks through the controlled stimulation of neighboring neurons. Because the laser stimulation can be performed much faster than can paired recording, it is also possible to search for synaptic connections between distant neurons that have a low probability of connectivity.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1525-8882
pubmed:author
pubmed:issnType
Electronic
pubmed:day
19
pubmed:volume
2002
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
pl2
pubmed:dateRevised
2009-10-21
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Infrared-guided laser stimulation of neurons in brain slices.
pubmed:affiliation
Max Planck Institute of Psychiatry, Munich, Federal Republic of Germany. dodt@mpipsykl.mpg.de
pubmed:publicationType
Journal Article, In Vitro