Source:http://linkedlifedata.com/resource/pubmed/id/11850923
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
2002-2-19
|
pubmed:abstractText |
This study was undertaken to investigate the possible pituitary-adrenal suppressive effects of triamcinolone acetonide under occlusive dressings in six psoriatic patients. Forty-five grams of a cream containing 0.1% triamcinolone acetonide was applied daily to the psoriatic lesions of four patients and covered with an occlusive dressing. Two patients received daily applications of 45 gm of 0.01% triamcinolone acetonide cream and occlusive dressings. The four patients who received the 0.1% triamcinolone acetonide applications showed a marked decrease in the 24-hour urinary 17-hydroxycorticosteroids and no significant response to intravenous metyrapone testing. The two patients who were treated with 0.01% triamcinolone acetonide also showed a significant decrease in 24-hour urinary 17-hydroxycorticosteroids, but a partial response to metyrapone testing. Percutaneous absorption of as little as 1 to 2 mg of triamcinolone acetonide may affect pituitary-adrenal function.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0003-987X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
92
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
174-7
|
pubmed:dateRevised |
2008-3-17
|
pubmed:meshHeading |
pubmed-meshheading:11850923-17-Hydroxycorticosteroids,
pubmed-meshheading:11850923-Administration, Topical,
pubmed-meshheading:11850923-Adult,
pubmed-meshheading:11850923-Aged,
pubmed-meshheading:11850923-Female,
pubmed-meshheading:11850923-Glucocorticoids,
pubmed-meshheading:11850923-Humans,
pubmed-meshheading:11850923-Male,
pubmed-meshheading:11850923-Middle Aged,
pubmed-meshheading:11850923-Occlusive Dressings,
pubmed-meshheading:11850923-Pituitary-Adrenal System,
pubmed-meshheading:11850923-Psoriasis,
pubmed-meshheading:11850923-Triamcinolone Acetonide
|
pubmed:year |
1965
|
pubmed:articleTitle |
Pituitary-adrenal function following topical triamcinolone acetonide and occlusion.
|
pubmed:affiliation |
Section of Dermatology, Department of Medicine, University of Chicago 60637, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|