Linked Life Data

11849426

Source:http://linkedlifedata.com/resource/pubmed/id/11849426

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2002-2-18
pubmed:abstractText
Nitric oxide and apoptosis in mesangial cells. Radicals such as nitric oxide (NO) or superoxide (O(-)(2)) encompass the ability to initiate morphological and biochemical alterations that are reminiscent of apoptosis. In mesangial cells, death as a result of NO formation is efficiently antagonized by the simultaneous presence of superoxide (O(-)(2)) and vice versa. This article reviews the consequences of a diffusion controlled NO/O(-)(2) interaction with the outcome of redirecting the apoptotic initiating activity of either NO or O(-)(2) toward protection. The crosstalk between cell destructive and protective pathways, and their activation or inhibition under the modulatory influence of NO and/or O(-)(2) are summarized.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0085-2538
pubmed:author
pubmed:issnType
Print
pubmed:volume
61
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
786-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Nitric oxide and apoptosis in mesangial cells.
pubmed:affiliation
Department of Cell Biology, University of Kaiserslautern, Erwin-Schrödinger-Strasse, 67663 Kaiserslautern, Germany. bruene@rhrk.uni-kl.de
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't