Linked Life Data

11847003

Source:http://linkedlifedata.com/resource/pubmed/id/11847003

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2002-2-15
pubmed:abstractText
Several reports have highlighted the biologic relevance of angiogenesis in neoplastic disorders and its potential impact on prognosis. In this review, we focus on recent findings about angiogenesis and angiogenetic factors in hematologic malignancies. We summarize the body of evidence supporting the hypothesis that a common progenitor gives rise to cells of both the endothelial and the hematopoietic lineages, and the current knowledge about the involvement of normal stromal cells in bone marrow angiogenesis. We also discuss the methodological aspects of microvessel count as a measure of tumor angiogenesis. Finally, we describe the current therapeutic role of angiogenesis inhibitors and possible future strategies involving these agents.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1525-8165
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
49-68
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
The role of angiogenesis in hematologic malignancies.
pubmed:affiliation
Department of Medical Sciences, Regina Apostolorum Hospital, Via S. Francesco 50, 00041 Albano Laziale, Italy. roberto.stasi@libero.it
pubmed:publicationType
Journal Article, Review