Linked Life Data

11842042

Source:http://linkedlifedata.com/resource/pubmed/id/11842042

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2002-2-13
pubmed:abstractText
The effects of maturation on cross-bridge (CB) properties were studied in rat diaphragm strips obtained at postnatal days 3, 10, and 17 and in adults (10-12 wk old). Calculations of muscle energetics and characteristics of CBs were determined from standard Huxley equations. Maturation did not change the curvature of the force-velocity relationship or the peak of mechanical efficiency. There was a significant increase in the total number of CBs per cross-sectional area (m) with aging but not in single CB force. The turnover rate of myosin ATPase increased, the duration of the CB cycle decreased, and the velocity of CBs decreased significantly only after the first week postpartum. There was a linear relationship between maximum total force and m (r = 0.969, P < 0.001), and between maximum unloaded shortening velocity and m (r = 0.728, P < 0.001). When this study in the rat and previous study in the hamster are compared, it appears that there are few species differences in the postnatal maturation process of the diaphragm.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
8750-7587
pubmed:author
pubmed:issnType
Print
pubmed:volume
92
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1074-82
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Effects of postnatal maturation on energetics and cross-bridge properties in rat diaphragm.
pubmed:affiliation
Department of Anesthesiology and Critical Care, Centre Hospitalo-Universitaire Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris, Université Paris V 75743 Paris Cedex 15, France. gorlia@club-internet.fr
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't