Linked Life Data

1183649

Source:http://linkedlifedata.com/resource/pubmed/id/1183649

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1976-1-16
pubmed:abstractText
Male mice were castrated on the day of birth or were treated with anti-gonadotropin serum (AGS) successively on days 1, 3, and 5 of age. When the adult AGS-treated males were compared with normal rabbit serum (NRS)-treated males with respect to fertility, male sexual behavior, gonadotropin release, body size, and penis size it was found that: (1) fertility of AGS-treated males did not differ from that of NRS-treated males; (2) AGS-treated males showed a significant reduction in penis size, compared with NRS-treated males; (3) both groups showed high levels of male sexual behavior; (4) neither group showed the capacity to support ovulation in ovarian grafts from immature mice. It was also observed that the fertility of female mice treated with AGS on days 1, 3, and 5 of age did not differ from that of control females treated with comparable doses of NRS. Male mice castrated at birth showed a significant reduction in male sexual behavior and penis size compared with males first sham-operated at birth then castrated at 25 days of age. Thus, males castrated at birth were similar to males receiving AGS in infancy, except for sex behavior. The results suggest that the neonatal pituitary in the mouse may not have an important role in the process of sexual differentiation. Previous data for the male rat were compared with those for the mouse.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0015-0282
pubmed:author
pubmed:issnType
Print
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
939-44
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Influence of neonatal castration or neonatal anti-gonadotropin treatment on fertility, phallus development, and male sexual behavior in the mouse.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.