rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
2002-2-8
|
pubmed:abstractText |
A lack of productive HIV-1 infection of Kit225 compared to Jurkat T cells, despite similar levels of CD4 and HIV-1 chemokine co-receptors, was found to correlate with the expression of vasoactive intestinal peptide/pituitary adenylate cyclase activating polypeptide receptor-1 (VPAC1). We therefore examined a role for this seven-transmembrane G protein-coupled neuroendocrine receptor in modulating HIV-1 infection.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0269-9370
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
16
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
309-19
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:11834941-Base Sequence,
pubmed-meshheading:11834941-Cell Line,
pubmed-meshheading:11834941-DNA, Antisense,
pubmed-meshheading:11834941-DNA, Complementary,
pubmed-meshheading:11834941-Gene Expression,
pubmed-meshheading:11834941-HIV Envelope Protein gp120,
pubmed-meshheading:11834941-HIV Infections,
pubmed-meshheading:11834941-HIV Long Terminal Repeat,
pubmed-meshheading:11834941-HIV-1,
pubmed-meshheading:11834941-Humans,
pubmed-meshheading:11834941-Jurkat Cells,
pubmed-meshheading:11834941-Receptors, Vasoactive Intestinal Peptide,
pubmed-meshheading:11834941-Receptors, Vasoactive Intestinal Polypeptide, Type I,
pubmed-meshheading:11834941-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:11834941-Signal Transduction,
pubmed-meshheading:11834941-T-Lymphocytes
|
pubmed:year |
2002
|
pubmed:articleTitle |
VPAC1 is a cellular neuroendocrine receptor expressed on T cells that actively facilitates productive HIV-1 infection.
|
pubmed:affiliation |
Department of Medicine, Institute of Medical Science, University of Toronto, Ontario, Canada.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|