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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2002-2-8
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pubmed:abstractText |
In humans, fasting leads to elevated serum GH concentrations. Traditionally, changes in hypothalamic GH-releasing hormone and somatostatin release are considered as the main mechanisms that induce this elevated GH secretion during fasting. Ghrelin is an endogenous ligand of the GH secretagogue receptor and is synthesized in the stomach. As ghrelin administration in man stimulates GH release, while serum ghrelin concentrations are elevated during fasting in man, this increase in ghrelin levels might be another mechanism whereby fasting results in stimulation of GH release.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Blood Glucose,
http://linkedlifedata.com/resource/pubmed/chemical/Fatty Acids, Nonesterified,
http://linkedlifedata.com/resource/pubmed/chemical/Ghrelin,
http://linkedlifedata.com/resource/pubmed/chemical/Human Growth Hormone,
http://linkedlifedata.com/resource/pubmed/chemical/Insulin,
http://linkedlifedata.com/resource/pubmed/chemical/Insulin-Like Growth Factor I,
http://linkedlifedata.com/resource/pubmed/chemical/Oligopeptides,
http://linkedlifedata.com/resource/pubmed/chemical/Peptide Hormones,
http://linkedlifedata.com/resource/pubmed/chemical/Peptides,
http://linkedlifedata.com/resource/pubmed/chemical/Placebos,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Somatotropin,
http://linkedlifedata.com/resource/pubmed/chemical/growth hormone releasing hexapeptide,
http://linkedlifedata.com/resource/pubmed/chemical/pegvisomant
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0804-4643
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
146
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
203-7
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:11834429-Adult,
pubmed-meshheading:11834429-Blood Glucose,
pubmed-meshheading:11834429-Circadian Rhythm,
pubmed-meshheading:11834429-Cross-Over Studies,
pubmed-meshheading:11834429-Double-Blind Method,
pubmed-meshheading:11834429-Fasting,
pubmed-meshheading:11834429-Fatty Acids, Nonesterified,
pubmed-meshheading:11834429-Ghrelin,
pubmed-meshheading:11834429-Human Growth Hormone,
pubmed-meshheading:11834429-Humans,
pubmed-meshheading:11834429-Insulin,
pubmed-meshheading:11834429-Insulin-Like Growth Factor I,
pubmed-meshheading:11834429-Kinetics,
pubmed-meshheading:11834429-Male,
pubmed-meshheading:11834429-Oligopeptides,
pubmed-meshheading:11834429-Peptide Hormones,
pubmed-meshheading:11834429-Peptides,
pubmed-meshheading:11834429-Placebos,
pubmed-meshheading:11834429-Receptors, Somatotropin
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pubmed:year |
2002
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pubmed:articleTitle |
Ghrelin drives GH secretion during fasting in man.
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pubmed:affiliation |
Division of Endocrinology, Department of Internal Medicine, Erasmus University Medical Centre, Rotterdam, The Netherlands. amuller@diakhuis.nl
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Controlled Clinical Trial,
Research Support, Non-U.S. Gov't
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