Source:http://linkedlifedata.com/resource/pubmed/id/11832206
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
2002-2-8
|
| pubmed:abstractText |
Defects in apoptosis underpin both tumorigenesis and drug resistance, and because of these defects chemotherapy often fails. Understanding the molecular events that contribute to drug-induced apoptosis, and how tumors evade apoptotic death, provides a paradigm to explain the relationship between cancer genetics and treatment sensitivity and should enable a more rational approach to anticancer drug design and therapy.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
0092-8674
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
25
|
| pubmed:volume |
108
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
153-64
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:11832206-Animals,
pubmed-meshheading:11832206-Antineoplastic Agents,
pubmed-meshheading:11832206-Apoptosis,
pubmed-meshheading:11832206-Drug Resistance, Neoplasm,
pubmed-meshheading:11832206-Humans,
pubmed-meshheading:11832206-Models, Biological,
pubmed-meshheading:11832206-Neoplasms,
pubmed-meshheading:11832206-Signal Transduction
|
| pubmed:year |
2002
|
| pubmed:articleTitle |
Apoptosis: a link between cancer genetics and chemotherapy.
|
| pubmed:affiliation |
Cancer Immunology Division, The Peter MacCallum Cancer Institute, Trescowthick Research Laboratories, Smorgon Family Building, St. Andrews Place, East Melbourne, 3002 Victoria, Australia. r.johnstone@pmci.unimelb.edu.au
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Review,
Research Support, Non-U.S. Gov't
|