Source:http://linkedlifedata.com/resource/pubmed/id/11820881
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
2002-1-31
|
| pubmed:abstractText |
The first convergent total synthesis of (+/-)-arisugacin A was accomplished by stereoselective construction of the arisugacin skeleton via a Knoevenagel-type reaction of an alpha,beta-unsaturated aldehyde with a 4-hydroxy 2-pyrone and stereoselective dihydroxylation followed by deoxygenation.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
1523-7060
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
7
|
| pubmed:volume |
4
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
367-9
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:11820881-Acetylcholinesterase,
pubmed-meshheading:11820881-Administration, Oral,
pubmed-meshheading:11820881-Biological Availability,
pubmed-meshheading:11820881-Cholinesterase Inhibitors,
pubmed-meshheading:11820881-Molecular Structure,
pubmed-meshheading:11820881-Pyrans,
pubmed-meshheading:11820881-Spectrum Analysis
|
| pubmed:year |
2002
|
| pubmed:articleTitle |
The first total synthesis of (+/-)-arisugacin A, a potent, orally bioavailable inhibitor of acetylcholinesterase.
|
| pubmed:affiliation |
The Kitasato Institute and School of Pharmaceutical Sciences, Kitasato University, Tokyo 108-8642, Japan. sunakuzat@pharma.kitasato-u.ac.jp
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|