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pubmed-article:11818671pubmed:abstractTextWe present a case of multiple myeloma who died of liver failure 7.5 months after initial diagnosis. Postmortem liver biopsy revealed diffuse CD3-expressing plasma cell infiltration and eosinophilic amorphous material deposition which was considered as light chain deposits. T cell receptor-gamma rearrangement was not detected in liver biopsy sections using the polymerase chain reaction despite CD3 positivity. To our knowledge, this is the first report of CD3-expressing plasma cell infiltration in tissue sections. The discordance between the phenotype and the genotype suggests a partial activation of genes encoding the T cell antigens by the transforming event. We also concluded that CD3 positivity was associated with short survival, which is consistent with previous data.lld:pubmed
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pubmed-article:11818671pubmed:authorpubmed-author:Ya?cíMünciMlld:pubmed
pubmed-article:11818671pubmed:authorpubmed-author:SucakGülsan...lld:pubmed
pubmed-article:11818671pubmed:authorpubmed-author:AkyolGülenGlld:pubmed
pubmed-article:11818671pubmed:authorpubmed-author:HaznedarRaufRlld:pubmed
pubmed-article:11818671pubmed:copyrightInfoCopyright 2002 S. Karger AG, Basellld:pubmed
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pubmed-article:11818671pubmed:volume107lld:pubmed
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pubmed-article:11818671pubmed:pagination38-42lld:pubmed
pubmed-article:11818671pubmed:dateRevised2004-11-17lld:pubmed
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pubmed-article:11818671pubmed:year2002lld:pubmed
pubmed-article:11818671pubmed:articleTitleHepatic failure due to CD3+ plasma cell infiltration of the liver in multiple myeloma.lld:pubmed
pubmed-article:11818671pubmed:affiliationDepartment of Haematology, Gazi Medical School, Gazi University, TR-06610 Ankara, Turkey. erhem@med.gazi.edu.trlld:pubmed
pubmed-article:11818671pubmed:publicationTypeJournal Articlelld:pubmed
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