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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2002-1-16
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pubmed:abstractText |
Rheumatoid synovitis is characterized by an invasive and tissue-destructive infiltrate of lymphocytes, macrophages and synoviocytes. Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) produced by these cells are important in the remodelling of the articular tissues in rheumatoid arthritis (RA). The aim of this study was to explore whether the serum concentrations of MMPs and their inhibitors were correlated with the histological appearance of the disease.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1462-0324
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
78-87
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pubmed:dateRevised |
2007-9-6
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pubmed:meshHeading |
pubmed-meshheading:11792884-Adult,
pubmed-meshheading:11792884-Aged,
pubmed-meshheading:11792884-Arthritis, Rheumatoid,
pubmed-meshheading:11792884-Biological Markers,
pubmed-meshheading:11792884-Biopsy, Needle,
pubmed-meshheading:11792884-Culture Techniques,
pubmed-meshheading:11792884-Female,
pubmed-meshheading:11792884-Humans,
pubmed-meshheading:11792884-Immunohistochemistry,
pubmed-meshheading:11792884-Male,
pubmed-meshheading:11792884-Matrix Metalloproteinase 1,
pubmed-meshheading:11792884-Matrix Metalloproteinases,
pubmed-meshheading:11792884-Middle Aged,
pubmed-meshheading:11792884-Probability,
pubmed-meshheading:11792884-Prognosis,
pubmed-meshheading:11792884-Sensitivity and Specificity,
pubmed-meshheading:11792884-Statistics, Nonparametric,
pubmed-meshheading:11792884-Synovitis,
pubmed-meshheading:11792884-Tissue Inhibitor of Metalloproteinase-1,
pubmed-meshheading:11792884-Tissue Inhibitor of Metalloproteinase-2,
pubmed-meshheading:11792884-Tissue Inhibitor of Metalloproteinases
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pubmed:year |
2002
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pubmed:articleTitle |
Serum matrix metalloproteinases and tissue inhibitors of metalloproteinases in different histological variants of rheumatoid synovitis.
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pubmed:affiliation |
Department of Rheumatology and Internal Diseases, Medical University of Bialystok, M.C. Sklodowskiej 24a, 15-276 Bialystok, Poland.
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pubmed:publicationType |
Journal Article,
Comparative Study
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