Linked Life Data

11755758

Source:http://linkedlifedata.com/resource/pubmed/id/11755758

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3-4
pubmed:dateCreated
2001-12-28
pubmed:abstractText
Enantiomer separations of various drugs by capillary electrophoresis (CE) were investigated utilizing carboxymethyl (CM) derivatives of some polysaccharides. Three types of CM-polysaccharides, namely CM-dextran, -amylose and -cellulose were employed as chiral selectors in the CE enantiomer separation. Capability of enantiomer separation by these CM-polysaccharides was compared with that by polysaccharides without CM residues (i.e. native or neutral polysaccharides). Among three selectors employed, CM-dextran and -cellulose showed a relatively wide capability of enantiomer separation. Modification of polysaccharides seems to lead to the enhancement of the capability of enantiomer separation. Degree of substitution greatly affected the capability of enantiomer separation of these polysaccharide derivatives as in the beta-cyclodextrins derivatives.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0731-7085
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
577-85
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Enantiomer separation by capillary electrophoresis utilizing carboxymethyl derivatives of polysaccharides as chiral selectors.
pubmed:affiliation
Analytical Chemistry Department, Product Technology Development Laboratory, Tanabe Seiyaku Co. Ltd., 16-89, Kashima 3-chome, Yodogawa-ku, Osaka 532-8505, Japan. nishi-h@tanabe.co.jp
pubmed:publicationType
Journal Article