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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2001-12-17
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pubmed:abstractText |
Osteoporosis is a sequela of hemopoietic cell transplantation with a complex multifactorial pathogenesis in which the relative role of chemotherapy and irradiation is not completely understood. Therefore, the authors investigated the toxicity of chemotherapy-only conditioning regimens on bone homeostasis and bone marrow osteoprogenitors, its dose dependency, and the mechanism of chemotherapy-induced osteopenia.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0008-543X
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2001 American Cancer Society.
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
92
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2419-28
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11745299-Adult,
pubmed-meshheading:11745299-Amenorrhea,
pubmed-meshheading:11745299-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:11745299-Bone Density,
pubmed-meshheading:11745299-Bone Diseases, Metabolic,
pubmed-meshheading:11745299-Bone Marrow Cells,
pubmed-meshheading:11745299-Bone Marrow Transplantation,
pubmed-meshheading:11745299-Breast Neoplasms,
pubmed-meshheading:11745299-Dose-Response Relationship, Drug,
pubmed-meshheading:11745299-Female,
pubmed-meshheading:11745299-Hematopoietic Stem Cells,
pubmed-meshheading:11745299-Homeostasis,
pubmed-meshheading:11745299-Humans,
pubmed-meshheading:11745299-Lymphoma, Non-Hodgkin,
pubmed-meshheading:11745299-Male,
pubmed-meshheading:11745299-Middle Aged,
pubmed-meshheading:11745299-Osteoporosis,
pubmed-meshheading:11745299-Transplantation Conditioning
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pubmed:year |
2001
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pubmed:articleTitle |
High-dose chemotherapy shows a dose-dependent toxicity to bone marrow osteoprogenitors: a mechanism for post-bone marrow transplantation osteopenia.
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pubmed:affiliation |
Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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