Source:http://linkedlifedata.com/resource/pubmed/id/11707636
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
2001-11-14
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pubmed:abstractText |
Several rat lines have been bred for their differences in alcohol consumption based on a continuous-access paradigm in which alcohol solution is available 24 hr/day. The limited-access paradigm (LAP), in which access to alcohol solution is restricted to a short period per day, however, has been used extensively to investigate the neurochemical mechanisms underlying alcohol consumption. There is evidence of possible differences in genetic determination of alcohol drinking in a continuous- versus limited-access condition. For these reasons, selective breeding for high- and low-alcohol consumption (HARF and LARF, respectively) based on a LAP was conducted.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0145-6008
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1613-20
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:11707636-Alcohol Drinking,
pubmed-meshheading:11707636-Animals,
pubmed-meshheading:11707636-Breeding,
pubmed-meshheading:11707636-Crosses, Genetic,
pubmed-meshheading:11707636-Ethanol,
pubmed-meshheading:11707636-Female,
pubmed-meshheading:11707636-Inbreeding,
pubmed-meshheading:11707636-Male,
pubmed-meshheading:11707636-Rats,
pubmed-meshheading:11707636-Selection, Genetic,
pubmed-meshheading:11707636-Self Administration
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pubmed:year |
2001
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pubmed:articleTitle |
Genetic selection for high and low alcohol consumption in a limited-access paradigm.
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pubmed:affiliation |
Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Ontario, Canada. anh_le@camh.net
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pubmed:publicationType |
Journal Article
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