Linked Life Data

1168870

Source:http://linkedlifedata.com/resource/pubmed/id/1168870

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1975-8-7
pubmed:abstractText
Permanent paralysis was induced in dogs by a 500 gram centimeter force injury on the spinal cord, and drug treatments were given 1 hour after injury and were continued for 3 days. Dogs were evaluated for 90 days. Isotonic saline or mannitol administration were ineffective in reversing the paralysis. In dogs receiving either dimethyl sulfoxide or dexamethasone, six of eight animals in the former and two of eight in the latter group regained partial or full recovery. The presence of somatosensory evoked responses taken before and at various intervals following trauma showed a good correlation in the prognostic recovery of each animal. It is concluded that dimethyl sulfoxide and dexamethasone can reverse a permanent experimental injury to the spinal cord when given within an hour after trauma.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0028-3878
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
508-14
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Pharmacologic treatment and evaluation of permanent experimental spinal cord trauma.
pubmed:publicationType
Journal Article, Comparative Study