Linked Life Data

11674832

Source:http://linkedlifedata.com/resource/pubmed/id/11674832

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2001-10-24
pubmed:abstractText
The Leksell stereotactic Gamma Knifetrade mark uses radiation from 201 (60)Co sources that are focused to the center of a collimator helmet to deliver a high dose of radiation with minimal irradiation of proximal structures. This paper presents a method for fast verification of the irradiation time as calculated by the Leksell Gamma Knifetrade mark treatment planning software GammaPlan((R)). To obtain the irradiation time for each shot in the treatment plan, one must first accurately calculate the tissue maximum ratio (TMR) for each of the individual 201 beams. The algorithm presented in this paper begins with the determination of the geometrical relationship between the Gamma Knifetrade mark collimator helmet and the stereotactic frame. A group of reference points is measured to build a head model simulating the patient skull geometry. During radiosurgery, the isocenter of the collimator helmet is moved to the shot center. A group of spatial vectors describing the reference points at the skull surface is obtained by converting the Cartesian coordinates to Polar coordinates. For each individual beam, the three nearest reference vectors are found by ranking the relative angles. The depth that each beam penetrates the patient's skull to the isocenter is obtained via linear interpolation. The TMR for each beam then is compared with the TMR for the calibration setup, which is done using a spherical 8 cm radius phantom. This algorithm is applied to verify the treatment time calculated in GammaPlan((R)) Version 5.2. The results are shown to agree with GammaPlan((R)) within 3%.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1526-9914
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
158-64
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Fast verification of Gamma Knifetrade mark treatment plans.
pubmed:affiliation
Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106, USA. pxz11@po.cwru.edu
pubmed:publicationType
Journal Article, Comparative Study, Validation Studies