Linked Life Data

11604092

Source:http://linkedlifedata.com/resource/pubmed/id/11604092

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5 Pt 2
pubmed:dateCreated
2001-10-17
pubmed:abstractText
A model with two stages and clonal expansion (TSCE) is reviewed as a prototype for biologically based models of cancer development. Applications of the TSCE model to data sets for animals and humans for particle radiation (alpha particles) are presented. The results suggest that the radiation not only influences the initiating mutation, but may also act as a promoter. A possible mechanism for the promoting action is described. The consequences of these results for the shapes of the radiation dose-response curves at low doses and dose rates are discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0033-7587
pubmed:author
pubmed:issnType
Print
pubmed:volume
156
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
678-81
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
The two-stage clonal expansion model as an example of a biologically based model of radiation-induced cancer.
pubmed:affiliation
GSF-Institute of Radiation Protection, 85758 Neuherberg, Germany. Heidenreich@gsf.de
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't