rdf:type |
|
lifeskim:mentions |
umls-concept:C0007595,
umls-concept:C0019682,
umls-concept:C0019699,
umls-concept:C0021756,
umls-concept:C0030705,
umls-concept:C0039194,
umls-concept:C0162638,
umls-concept:C0205217,
umls-concept:C0332281,
umls-concept:C1332714,
umls-concept:C1511572,
umls-concept:C1521828
|
pubmed:issue |
14
|
pubmed:dateCreated |
2001-10-1
|
pubmed:abstractText |
In an attempt to determine the mechanisms underlying the CD4 T cell expansions in patients receiving intermittent interleukin (IL)-2, a cohort of 10 HIV infected patients were studied during a 5-day cycle of IL-2 to measure rates of apoptosis, the expression of activation markers in CD4 and CD8 T cell subsets and the serum levels of proinflammatory cytokines. All patients were receiving highly active antiretroviral therapy.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0269-9370
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
28
|
pubmed:volume |
15
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1765-75
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:11579237-Antiretroviral Therapy, Highly Active,
pubmed-meshheading:11579237-Apoptosis,
pubmed-meshheading:11579237-CD4-Positive T-Lymphocytes,
pubmed-meshheading:11579237-CD8-Positive T-Lymphocytes,
pubmed-meshheading:11579237-Cytokines,
pubmed-meshheading:11579237-Female,
pubmed-meshheading:11579237-HIV Infections,
pubmed-meshheading:11579237-HIV-1,
pubmed-meshheading:11579237-Humans,
pubmed-meshheading:11579237-Immunophenotyping,
pubmed-meshheading:11579237-Interleukin-2,
pubmed-meshheading:11579237-Lymphocyte Activation,
pubmed-meshheading:11579237-Male,
pubmed-meshheading:11579237-Receptors, Interleukin-2,
pubmed-meshheading:11579237-Viral Load
|
pubmed:year |
2001
|
pubmed:articleTitle |
CD4 T cell expansions are associated with increased apoptosis rates of T lymphocytes during IL-2 cycles in HIV infected patients.
|
pubmed:affiliation |
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda MD 20892, USA.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.
|