|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
7
|
|
pubmed:dateCreated |
2001-10-1
|
|
pubmed:abstractText |
We investigated a correlation between the expression of human sodium iodide symporter (hNIS) mRNA and the uptake of 99mTc-pertechnetate in 25 breast tumors. 99mTc-pertechnetate scintigraphy revealed positive uptake in 4 patients. The normalized mRNA expression of hNIS was higher in tumors with positive uptake on the scintigraphy (n=4, median 0.97, range 0.78-1.27) than that in negative uptake tumors (n=21, median 0.46, range 0.10-1.03, p < 0.005). 99mTc-pertechnetate uptake is correlated with the hNIS expression in the breast tumor.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
0969-8051
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
28
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
829-34
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:11578905-Breast Neoplasms,
pubmed-meshheading:11578905-Female,
pubmed-meshheading:11578905-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:11578905-Humans,
pubmed-meshheading:11578905-Middle Aged,
pubmed-meshheading:11578905-RNA, Messenger,
pubmed-meshheading:11578905-Radiopharmaceuticals,
pubmed-meshheading:11578905-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:11578905-Sodium Pertechnetate Tc 99m,
pubmed-meshheading:11578905-Symporters
|
|
pubmed:year |
2001
|
|
pubmed:articleTitle |
Correlation between 99mTc-pertechnetate uptakes and expressions of human sodium iodide symporter gene in breast tumor tissues.
|
|
pubmed:affiliation |
Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea. dhmoon@amc.seoul.kr
|
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
|
