Linked Life Data

11561968

Source:http://linkedlifedata.com/resource/pubmed/id/11561968

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2001-9-19
pubmed:abstractText
The epidemiology and transmission dynamics of sheep scrapie is as yet poorly understood. Here we present a theoretical analysis of the transmission dynamics within a sheep flock, concentrating on how persistence properties depend on transmission scenario and flock size. Patterns of disease persistence and extinction are studied analytically using branching-process approximations and numerically using stochastic model simulations. For a given basic reproduction number, disease extinction is most likely when late-stage infected animals are responsible for most of the transmission. This effect can be understood in terms of aggregation in the distribution of the number of secondary infections arising from a single primary infection. The presence of an environmental reservoir reduces the probability of extinction.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0950-2688
pubmed:author
pubmed:issnType
Print
pubmed:volume
127
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
157-67
pubmed:dateRevised
2010-5-17
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Persistence patterns of scrapie in a sheep flock.
pubmed:affiliation
Wellcome Trust Centre for the Epidemiology of Infectious Disease, Department of Zoology, University of Oxford, United Kingdom.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't