Linked Life Data

1155097

Source:http://linkedlifedata.com/resource/pubmed/id/1155097

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1975-11-7
pubmed:abstractText
Tissue from 40 oral premalignant lesions were investigated for the presence of blood group antigens A and B. The material included 18 leukoplakias, 1 erythroplakia, and 3 lichen planus, all with varying degrees of epithelial dysplasia, and 18 leukoplakias without histological evidence of impending malignancy. Thirty-eight benign keratotic oral muscosal lesions were included as a control group. The antigens were demonstrated by a double layer immunofluorescence technique, and the reactivity was compared, by titration, to the reactivity of adjacent normal epithelium from the same patient. All 22 lesions with dysplsia showed decreased reactivity for blood group antigen. Among the 18 leukoplakias without any signs of impending malignancy 4 cases demonstrated loss of antigen reactivity. None of 38 benign control lesions showed any change in antigen reactivity as compared to normal adjacent epithelium.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0365-4184
pubmed:author
pubmed:issnType
Print
pubmed:volume
83
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
292-300
pubmed:dateRevised
2009-6-4
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Loss of epithelial blood group antigens A and B in oral premalignant lesions.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.