| pubmed-article:11536623 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11536623 | lifeskim:mentions | umls-concept:C0028630 | lld:lifeskim |
| pubmed-article:11536623 | lifeskim:mentions | umls-concept:C0032550 | lld:lifeskim |
| pubmed-article:11536623 | lifeskim:mentions | umls-concept:C0001674 | lld:lifeskim |
| pubmed-article:11536623 | lifeskim:mentions | umls-concept:C0055863 | lld:lifeskim |
| pubmed-article:11536623 | lifeskim:mentions | umls-concept:C0205679 | lld:lifeskim |
| pubmed-article:11536623 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:11536623 | pubmed:dateCreated | 1999-9-9 | lld:pubmed |
| pubmed-article:11536623 | pubmed:abstractText | The binding of adenine derivatives to Na(+)-montmorillonite increases in the order 5'AMP, 3'-AMP, 5'ADP < adenosine < purine, adenine. With the exception of cytosine, cytosine derivatives bind less strongly than the corresponding adenine derivatives in the order 5'-CMP < cytidine < cytosine. There is little difference in the binding of uracil derivatives and these compounds bind less strongly than the corresponding adenine analogs. It is concluded that the adenine ring in adenine derivatives is protonated by the acidic montmorillonite surface and binding is a consequence of the electrostatic interaction between the protonated base and the negative charges on the surface of the montmorillonite. Different binding trends were observed with Cu(2+)-montmorillonite with AMP binding more strongly than adenosine and UMP binding more strongly than uridine. It is concluded that ligation to the Cu2+ is a major force in the binding of nucleotides to Cu(2+)-montmorillonite and are not readily washed from the clay. Factors contributing to the binding are discussed. Watson-Crick hydrogen bonding of 5'-AMP to poly(U) and 5'GMP to poly(C) was observed when the homopolymers are bound to the surface of the clay. No association of 5'-UMP to poly(U) bound to clay was detected. The possible role of montmorillonite clays in the prebiotic formation of RNA is discussed. | lld:pubmed |
| pubmed-article:11536623 | pubmed:keyword | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11536623 | pubmed:keyword | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11536623 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11536623 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11536623 | pubmed:citationSubset | S | lld:pubmed |
| pubmed-article:11536623 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11536623 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11536623 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11536623 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11536623 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11536623 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11536623 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11536623 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11536623 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11536623 | pubmed:issn | 0169-6149 | lld:pubmed |
| pubmed-article:11536623 | pubmed:author | pubmed-author:FerrisJ PJP | lld:pubmed |
| pubmed-article:11536623 | pubmed:author | pubmed-author:AgarwalV KVK | lld:pubmed |
| pubmed-article:11536623 | pubmed:author | pubmed-author:ErtemGG | lld:pubmed |
| pubmed-article:11536623 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11536623 | pubmed:volume | 19 | lld:pubmed |
| pubmed-article:11536623 | pubmed:owner | NASA | lld:pubmed |
| pubmed-article:11536623 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11536623 | pubmed:pagination | 153-64 | lld:pubmed |
| pubmed-article:11536623 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:11536623 | pubmed:meshHeading | pubmed-meshheading:11536623... | lld:pubmed |
| pubmed-article:11536623 | pubmed:meshHeading | pubmed-meshheading:11536623... | lld:pubmed |
| pubmed-article:11536623 | pubmed:meshHeading | pubmed-meshheading:11536623... | lld:pubmed |
| pubmed-article:11536623 | pubmed:meshHeading | pubmed-meshheading:11536623... | lld:pubmed |
| pubmed-article:11536623 | pubmed:meshHeading | pubmed-meshheading:11536623... | lld:pubmed |
| pubmed-article:11536623 | pubmed:meshHeading | pubmed-meshheading:11536623... | lld:pubmed |
| pubmed-article:11536623 | pubmed:meshHeading | pubmed-meshheading:11536623... | lld:pubmed |
| pubmed-article:11536623 | pubmed:meshHeading | pubmed-meshheading:11536623... | lld:pubmed |
| pubmed-article:11536623 | pubmed:meshHeading | pubmed-meshheading:11536623... | lld:pubmed |
| pubmed-article:11536623 | pubmed:meshHeading | pubmed-meshheading:11536623... | lld:pubmed |
| pubmed-article:11536623 | pubmed:meshHeading | pubmed-meshheading:11536623... | lld:pubmed |
| pubmed-article:11536623 | pubmed:meshHeading | pubmed-meshheading:11536623... | lld:pubmed |
| pubmed-article:11536623 | pubmed:meshHeading | pubmed-meshheading:11536623... | lld:pubmed |
| pubmed-article:11536623 | pubmed:meshHeading | pubmed-meshheading:11536623... | lld:pubmed |
| pubmed-article:11536623 | pubmed:meshHeading | pubmed-meshheading:11536623... | lld:pubmed |
| pubmed-article:11536623 | pubmed:meshHeading | pubmed-meshheading:11536623... | lld:pubmed |
| pubmed-article:11536623 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:11536623 | pubmed:articleTitle | The adsorption of nucleotides and polynucleotides on montmorillonite clay. | lld:pubmed |
| pubmed-article:11536623 | pubmed:affiliation | Department of Chemistry, Rensselaer Polytechnic Institute, Troy, NY 12180, USA. | lld:pubmed |
| pubmed-article:11536623 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11536623 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11536623 | lld:pubmed |
