rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
17
|
pubmed:dateCreated |
2001-8-30
|
pubmed:abstractText |
A synthesis program directed toward improving the stability of imidoyl thiourea based non-nucleoside reverse transcriptase inhibitors (NNRTIs) led to the discovery of diaryltriazines (DATAs), a new class of potent NNRTIs. The synthesis and anti-HIV structure-activity relationship (SAR) studies of a series of DATA derivatives are described.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0960-894X
|
pubmed:author |
pubmed-author:AndriesKK,
pubmed-author:ArnoldEE,
pubmed-author:AzijnHH,
pubmed-author:DaeyaertF FFF,
pubmed-author:DasKK,
pubmed-author:De CorteB LBL,
pubmed-author:HeeresJJ,
pubmed-author:HoC YCY,
pubmed-author:JanssenP APA,
pubmed-author:KavashR WRW,
pubmed-author:KoymansL MLM,
pubmed-author:KuklaM JMJ,
pubmed-author:LewiP JPJ,
pubmed-author:LudoviciD WDW,
pubmed-author:MoereelsH EHE,
pubmed-author:PauwelsRR,
pubmed-author:Van AkenK JKJ,
pubmed-author:YuXX,
pubmed-author:de BéthuneM PMP,
pubmed-author:de JongeM RMR
|
pubmed:issnType |
Print
|
pubmed:day |
3
|
pubmed:volume |
11
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
2229-34
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
|
pubmed:year |
2001
|
pubmed:articleTitle |
Evolution of anti-HIV drug candidates. Part 2: Diaryltriazine (DATA) analogues.
|
pubmed:affiliation |
Janssen Research Foundation, Welsh and McKean Roads, Spring House, PA 19477, USA.
|
pubmed:publicationType |
Journal Article
|