pubmed-article:11514145 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:11514145 | lifeskim:mentions | umls-concept:C0085104 | lld:lifeskim |
pubmed-article:11514145 | lifeskim:mentions | umls-concept:C0184511 | lld:lifeskim |
pubmed-article:11514145 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
pubmed-article:11514145 | lifeskim:mentions | umls-concept:C0220825 | lld:lifeskim |
pubmed-article:11514145 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
pubmed-article:11514145 | lifeskim:mentions | umls-concept:C0243072 | lld:lifeskim |
pubmed-article:11514145 | pubmed:issue | 16 | lld:pubmed |
pubmed-article:11514145 | pubmed:dateCreated | 2001-8-21 | lld:pubmed |
pubmed-article:11514145 | pubmed:abstractText | The 17-methoxy group of geldanamycin was substituted with 1,3-diaminopropane and 1,3-diamino-2-hydroxypropane to introduce a primary amino group useful for conjugation with targeting moieties and drug carriers. We have developed a procedure that has provided improved yield and reproducibility of the syntheses. Both geldanamycin derivatives demonstrated antiproliferative activity towards the human ovarian carcinoma cell line, A2780. | lld:pubmed |
pubmed-article:11514145 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11514145 | pubmed:language | eng | lld:pubmed |
pubmed-article:11514145 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11514145 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:11514145 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11514145 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11514145 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11514145 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11514145 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11514145 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11514145 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11514145 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11514145 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:11514145 | pubmed:month | Aug | lld:pubmed |
pubmed-article:11514145 | pubmed:issn | 0960-894X | lld:pubmed |
pubmed-article:11514145 | pubmed:author | pubmed-author:KasuyaYY | lld:pubmed |
pubmed-article:11514145 | pubmed:author | pubmed-author:NGJJ | lld:pubmed |
pubmed-article:11514145 | pubmed:author | pubmed-author:KopecekJJ | lld:pubmed |
pubmed-article:11514145 | pubmed:author | pubmed-author:KopeckováPP | lld:pubmed |
pubmed-article:11514145 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:11514145 | pubmed:day | 20 | lld:pubmed |
pubmed-article:11514145 | pubmed:volume | 11 | lld:pubmed |
pubmed-article:11514145 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:11514145 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:11514145 | pubmed:pagination | 2089-91 | lld:pubmed |
pubmed-article:11514145 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
pubmed-article:11514145 | pubmed:meshHeading | pubmed-meshheading:11514145... | lld:pubmed |
pubmed-article:11514145 | pubmed:meshHeading | pubmed-meshheading:11514145... | lld:pubmed |
pubmed-article:11514145 | pubmed:meshHeading | pubmed-meshheading:11514145... | lld:pubmed |
pubmed-article:11514145 | pubmed:meshHeading | pubmed-meshheading:11514145... | lld:pubmed |
pubmed-article:11514145 | pubmed:meshHeading | pubmed-meshheading:11514145... | lld:pubmed |
pubmed-article:11514145 | pubmed:meshHeading | pubmed-meshheading:11514145... | lld:pubmed |
pubmed-article:11514145 | pubmed:meshHeading | pubmed-meshheading:11514145... | lld:pubmed |
pubmed-article:11514145 | pubmed:meshHeading | pubmed-meshheading:11514145... | lld:pubmed |
pubmed-article:11514145 | pubmed:meshHeading | pubmed-meshheading:11514145... | lld:pubmed |
pubmed-article:11514145 | pubmed:meshHeading | pubmed-meshheading:11514145... | lld:pubmed |
pubmed-article:11514145 | pubmed:year | 2001 | lld:pubmed |
pubmed-article:11514145 | pubmed:articleTitle | Improved synthesis and evaluation of 17-substituted aminoalkylgeldanamycin derivatives applicable to drug delivery systems. | lld:pubmed |
pubmed-article:11514145 | pubmed:affiliation | Department of Pharmaceutics and Pharmaceutical Chemistry/CCCD, University of Utah, Salt Lake City, UT 84112, USA. | lld:pubmed |
pubmed-article:11514145 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:11514145 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:11514145 | lld:chembl |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11514145 | lld:pubmed |