Source:http://linkedlifedata.com/resource/pubmed/id/11513850
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2001-8-21
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pubmed:abstractText |
We have identified an Arabidopsis thaliana cDNA, designated as AtTBP1, encoding a protein with a predicted size of 70.6 kDa that specifically binds to the plant telomeric repeat sequence TTTAGGG. AtTBP1 is present as a single-copy gene in Arabidopsis genome and is expressed ubiquitously in various organs. AtTBP1 has a single Myb telomeric DNA binding domain at the C-terminus and an extensive homology with other known telomere-binding proteins. The isolated C-terminus of AtTBP1 is capable of sequence-specific DNA binding to plant duplex telomeric DNA. These results suggest that AtTBP1 may play important roles in plant telomere function in vivo.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0014-5793
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
10
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pubmed:volume |
503
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
35-40
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11513850-Amino Acid Sequence,
pubmed-meshheading:11513850-Arabidopsis,
pubmed-meshheading:11513850-Arabidopsis Proteins,
pubmed-meshheading:11513850-Base Sequence,
pubmed-meshheading:11513850-Cloning, Molecular,
pubmed-meshheading:11513850-DNA, Complementary,
pubmed-meshheading:11513850-DNA-Binding Proteins,
pubmed-meshheading:11513850-Molecular Sequence Data,
pubmed-meshheading:11513850-Protein Binding,
pubmed-meshheading:11513850-Repetitive Sequences, Nucleic Acid,
pubmed-meshheading:11513850-Sequence Homology, Amino Acid
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pubmed:year |
2001
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pubmed:articleTitle |
Sequence-specific binding property of Arabidopsis thaliana telomeric DNA binding protein 1 (AtTBP1).
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pubmed:affiliation |
Department of Biology, Yonsei University, 120-749, Seoul, South Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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