Linked Life Data

11513562

Source:http://linkedlifedata.com/resource/pubmed/id/11513562

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2001-8-21
pubmed:abstractText
Metastasis can occur many years after primary tumour treatment. However, the status of the tumour during this period of dormancy is poorly understood. As part of our ongoing experimental studies on mechanisms of metastasis, we have discovered that large numbers of disseminated single cells may persist in secondary sites for extended time periods. Identification of these cells was facilitated by in vivo techniques developed to quantify the fate of individual cells during the metastatic process. Here we review these in vivo techniques and findings. We also discuss the potential clinical implications if dormant solitary cells exist in appreciable numbers in cancer patients.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1044-579X
pubmed:author
pubmed:copyrightInfo
Copyright 2001 Academic Press.
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
271-6
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Solitary cancer cells as a possible source of tumour dormancy?
pubmed:affiliation
Medical Biophysics Department, University of Western Ontario, London, Ontario, Canada N6A 5C1.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Review, Research Support, Non-U.S. Gov't