Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1975-11-6
|
pubmed:abstractText |
Pharmacokinetics of intramuscular gentamicin was observed in healty rats, in rats with renal parenchyma reduced to 1/5 of normal and in rats after bilateral nephrectomy. The results obtained support the assumption that in rats gentamicin is excreted only through the kidneys. Reduction of the renal parenchyma to 1/5 of normal is associated with extention of biological half-life only to double the control value. The results support the hypothesis that in the given experimental conditions gentamicin excretion in residual nephrons increases.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0340-0026
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
11
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1-6
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:1150358-Animals,
pubmed-meshheading:1150358-Biological Assay,
pubmed-meshheading:1150358-Gentamicins,
pubmed-meshheading:1150358-Half-Life,
pubmed-meshheading:1150358-Kidney,
pubmed-meshheading:1150358-Kinetics,
pubmed-meshheading:1150358-Male,
pubmed-meshheading:1150358-Nephrectomy,
pubmed-meshheading:1150358-Organ Size,
pubmed-meshheading:1150358-Rats
|
pubmed:year |
1975
|
pubmed:articleTitle |
Gentamicin pharmacokinetics in rats with reduced renal parenchyma.
|
pubmed:publicationType |
Journal Article,
Comparative Study
|