Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2001-8-1
pubmed:abstractText
A murine toxoplasmosis model has been developed that results in central nervous system (CNS) and ocular inflammation characterized by encephalitis with numerous brain tissue cysts and milder inflammation with rare tissue cysts in the eye after 4 weeks of Toxoplasma gondii infection. In this model IFN gamma and inducible nitric oxide (iNO) are protective against T. gondii infection. In this study, the role of apoptosis in the pathogenesis of toxoplasmosis was investigated.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0146-0404
pubmed:author
pubmed:issnType
Print
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2031-6
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed-meshheading:11481268-Animals, pubmed-meshheading:11481268-Antigens, CD95, pubmed-meshheading:11481268-Apoptosis, pubmed-meshheading:11481268-Brain, pubmed-meshheading:11481268-Fas Ligand Protein, pubmed-meshheading:11481268-Immunoenzyme Techniques, pubmed-meshheading:11481268-In Situ Nick-End Labeling, pubmed-meshheading:11481268-Interferon-gamma, pubmed-meshheading:11481268-Membrane Glycoproteins, pubmed-meshheading:11481268-Mice, pubmed-meshheading:11481268-Mice, Inbred BALB C, pubmed-meshheading:11481268-Mice, Inbred MRL lpr, pubmed-meshheading:11481268-Nitrites, pubmed-meshheading:11481268-Proto-Oncogene Proteins, pubmed-meshheading:11481268-Proto-Oncogene Proteins c-bcl-2, pubmed-meshheading:11481268-RNA, Messenger, pubmed-meshheading:11481268-Retina, pubmed-meshheading:11481268-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:11481268-Toxoplasma, pubmed-meshheading:11481268-Toxoplasmosis, Animal, pubmed-meshheading:11481268-Toxoplasmosis, Cerebral, pubmed-meshheading:11481268-Toxoplasmosis, Ocular, pubmed-meshheading:11481268-bcl-2-Associated X Protein
pubmed:year
2001
pubmed:articleTitle
Involvement of apoptosis and interferon-gamma in murine toxoplasmosis.
pubmed:affiliation
Section of Immunopathology, Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892-1857, USA.
pubmed:publicationType
Journal Article