Linked Life Data

11464992

Source:http://linkedlifedata.com/resource/pubmed/id/11464992

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2001-7-23
pubmed:abstractText
Autoimmune hemolytic anemia (AIHA) is a hematologic disorder that is rarely seen in infants and young children. Most cases are associated with viral or bacterial infection, but the immunologic events leading to hemolysis are poorly understood. We describe two infants with severe cytomegalovirus (CMV)-associated warm antibody AIHA. One case was immunohematologically analyzed and showed suggestive evidence that endogenous anti-CMV IgG antibodies were the pathogenic antibodies leading to hemolysis, implicating a possible causal relationship between AIHA and CMV infection. Both patients were ultimately treated with intravenous CMV immune globulin, with subsequent improvement. These cases suggest that investigation for the presence of CMV in infantile AIHA is warranted and that CMV immune globulin should be considered as a therapeutic option.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1077-4114
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
318-20
pubmed:dateRevised
2011-10-6
pubmed:meshHeading
pubmed:articleTitle
Infantile cytomegalovirus-associated autoimmune hemolytic anemia.
pubmed:affiliation
Hematology and Oncology Center, Cook Children's Medical Center, Fort Worth, Texas 76104, USA. jmurray@cookchildrens.org
pubmed:publicationType
Journal Article, Case Reports