|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
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|
pubmed:dateCreated |
2001-7-18
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|
pubmed:abstractText |
Coadministration of thalidomide, cyproheptadine or diclofenac has been shown to increase the area under the plasma concentration-time curve (AUC) of the novel antitumour agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in mice. The aim of this study was to further investigate these pharmacokinetic DMXAA-drug interactions in the rat model.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
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|
pubmed:status |
MEDLINE
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pubmed:month |
Jun
|
|
pubmed:issn |
0344-5704
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
47
|
|
pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
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pubmed:pagination |
541-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11459209-Animals,
pubmed-meshheading:11459209-Antineoplastic Agents,
pubmed-meshheading:11459209-Cyproheptadine,
pubmed-meshheading:11459209-Diclofenac,
pubmed-meshheading:11459209-Drug Interactions,
pubmed-meshheading:11459209-Glucuronides,
pubmed-meshheading:11459209-Hydroxylation,
pubmed-meshheading:11459209-Male,
pubmed-meshheading:11459209-Mice,
pubmed-meshheading:11459209-Microsomes, Liver,
pubmed-meshheading:11459209-Rats,
pubmed-meshheading:11459209-Rats, Wistar,
pubmed-meshheading:11459209-Thalidomide,
pubmed-meshheading:11459209-Xanthenes,
pubmed-meshheading:11459209-Xanthones
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|
pubmed:year |
2001
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|
pubmed:articleTitle |
A difference between the rat and mouse in the pharmacokinetic interaction of 5,6-dimethylxanthenone-4-acetic acid with thalidomide.
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pubmed:affiliation |
Department of Pharmacology and Clinical Pharmacology, The University of Auckland School of Medicine, New Zealand.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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