Source:http://linkedlifedata.com/resource/pubmed/id/11454247
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2001-7-16
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pubmed:abstractText |
The population structure of Onchocerca volvulus macrofilariae was studied in villages of central Cameroon where onchocerciasis is hyper-endemic. One nodule selected at random was removed from each of 576 adult males, and examined by histology. The numbers of male and female worms/nodule, and the status of the female worms (fecund, non-fecund, or dead) were recorded. The observations were analysed to evaluate whether the mean numbers of worms of each category varied in relation to the patient's age, the level of endemicity in his village, the anatomical localization of the nodule, the weight of the nodule, and the total number of palpable nodules harboured by the patient. The results obtained were very similar to those reported from West Africa. The mean numbers of dead female worms/nodule were relatively high in the villages with the lowest levels of endemicity. The mean numbers of fecund females and of live males were significantly higher in the nodules located around the knees. These results provide information which might be useful in modelling the population dynamics of O. volvulus, and also in the context of trials of any potentially macrofilaricidal drugs.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0003-4983
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
95
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
379-88
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pubmed:dateRevised |
2009-5-18
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pubmed:meshHeading |
pubmed-meshheading:11454247-Adolescent,
pubmed-meshheading:11454247-Adult,
pubmed-meshheading:11454247-Age Factors,
pubmed-meshheading:11454247-Animals,
pubmed-meshheading:11454247-Cameroon,
pubmed-meshheading:11454247-Endemic Diseases,
pubmed-meshheading:11454247-Female,
pubmed-meshheading:11454247-Fertility,
pubmed-meshheading:11454247-Humans,
pubmed-meshheading:11454247-Male,
pubmed-meshheading:11454247-Middle Aged,
pubmed-meshheading:11454247-Onchocerca volvulus,
pubmed-meshheading:11454247-Onchocerciasis,
pubmed-meshheading:11454247-Paraffin Embedding,
pubmed-meshheading:11454247-Population Dynamics,
pubmed-meshheading:11454247-Statistics, Nonparametric
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pubmed:year |
2001
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pubmed:articleTitle |
Studies on the macrofilarial population of Onchocerca volvulus in hyper-endemic villages of the Central province of Cameroon.
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pubmed:affiliation |
Laboratoire mixte IRD-CPC d'Epidémiologie et de Santé publique, Centre Pasteur du Cameroun, B.P. 1274, Yaoundé, Cameroon. orstom.cpc@camnet.cm
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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