Source:http://linkedlifedata.com/resource/pubmed/id/11453589
Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
2001-7-16
|
| pubmed:abstractText |
A surveillance program for invasive pneumococcal disease was undertaken in Puyde-D?me, an administrative district of the region Auvergne in France, from 1 January 1994 to 31 December 1998. A total of 214 cases were identified. The annual incidence of invasive pneumococcal disease increased (P=0.04) from 5.5 in 1994 to 9.3 cases per 10(5) person-years in 1998. The highest incidences were for children <2 years of age (59.2 cases per 10(5) person-years) and for adults > or = 65 years (18 cases per 10(5) person-years). Clinical diagnoses, available in 200 patients, included acute pneumonia (62%), meningitis (10%), sepsis without focus (20%), and others (8%). The most frequent chronic medical conditions of the patients included smoking, alcoholism, cardiovascular and pulmonary diseases, and malignancies. Thirty-one percent of the isolates were nonsusceptible to penicillin. Penicillin resistance (MIC > or = 0.1 mg/l) was more frequent (P=0.02) in cancer patients. The overall case-fatality rate was 21.5%. Risk factors for death were age, sex, and underlying diseases of the patients, along with the severity of illness. These population-based findings should convince clinicians to offer pneumococcal vaccine to patients at high risk for invasive pneumococcal disease, thereby increasing vaccination coverage levels in France.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0934-9723
|
| pubmed:author |
pubmed-author:AndréMM,
pubmed-author:BeytoutJJ,
pubmed-author:CaillaudDD,
pubmed-author:De ChampsCC,
pubmed-author:GuólonDD,
pubmed-author:LabbéAA,
pubmed-author:LaurichesseHH,
pubmed-author:NguyenL TLT,
pubmed-author:PoirierVV,
pubmed-author:RomaszkoJ PJP,
pubmed-author:RuivardMM,
pubmed-author:SouweineBB
|
| pubmed:issnType |
Print
|
| pubmed:volume |
20
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
299-308
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:11453589-Adolescent,
pubmed-meshheading:11453589-Adult,
pubmed-meshheading:11453589-Age Distribution,
pubmed-meshheading:11453589-Aged,
pubmed-meshheading:11453589-Child,
pubmed-meshheading:11453589-Child, Preschool,
pubmed-meshheading:11453589-Drug Resistance,
pubmed-meshheading:11453589-Female,
pubmed-meshheading:11453589-France,
pubmed-meshheading:11453589-Humans,
pubmed-meshheading:11453589-Incidence,
pubmed-meshheading:11453589-Infant,
pubmed-meshheading:11453589-Male,
pubmed-meshheading:11453589-Microbial Sensitivity Tests,
pubmed-meshheading:11453589-Middle Aged,
pubmed-meshheading:11453589-Pneumococcal Infections,
pubmed-meshheading:11453589-Population Surveillance,
pubmed-meshheading:11453589-Risk Factors,
pubmed-meshheading:11453589-Serotyping,
pubmed-meshheading:11453589-Streptococcus pneumoniae
|
| pubmed:year |
2001
|
| pubmed:articleTitle |
Clinical characteristics and outcome of patients with invasive pneumococcal disease, Puy-de-Dôme, France, 1994-1998.
|
| pubmed:affiliation |
Infectious Diseases Department, Hôtel-Dieu, University Hospital of Clermont-Ferrand, France. hlaurichesse@chu-clermontferrand.fr
|
| pubmed:publicationType |
Journal Article
|