Source:http://linkedlifedata.com/resource/pubmed/id/11433188
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2001-7-3
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pubmed:abstractText |
Extracellular ATP signaling affects the cells of renal glomeruli via activation of P2-purinoceptors, denoted as P2X and P2Y. Through either of these purinoceptors, ATP is able to stimulate an increase in intracellular [Ca2+]. P2Y-receptors are expressed on mesangial and endothelial cells, thus may participate in contraction and relaxation of glomeruli, respectively. Moreover, P2Y-receptors possess activity of ecto-ATPase which may lead to dephosphorylation of ATP and generation of adenosine. The aim of the present study was to investigate the involvement of P2Y-receptors in responses of renal glomeruli to extracellular ATP.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1234-1010
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
635-340
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pubmed:dateRevised |
2010-3-23
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pubmed:meshHeading |
pubmed-meshheading:11433188-Adenosine Triphosphate,
pubmed-meshheading:11433188-Animals,
pubmed-meshheading:11433188-Kidney Glomerulus,
pubmed-meshheading:11433188-Male,
pubmed-meshheading:11433188-Phosphorylation,
pubmed-meshheading:11433188-Rats,
pubmed-meshheading:11433188-Rats, Wistar,
pubmed-meshheading:11433188-Receptors, Purinergic P2
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pubmed:articleTitle |
The role of P2Y-receptors in the regulation of glomerular volume.
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pubmed:affiliation |
Department of Clinical Chemistry, Medical University of Gda?sk, Poland. majank@amg.gda.pl
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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