|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0021364,
umls-concept:C0026882,
umls-concept:C0205314,
umls-concept:C0332281,
umls-concept:C0679622,
umls-concept:C0682969,
umls-concept:C1367578,
umls-concept:C1514562,
umls-concept:C1880389,
umls-concept:C1883204,
umls-concept:C1883221
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|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2001-6-25
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|
pubmed:abstractText |
Resistance to androgens has been suggested as a possible cause of male infertility. This hypothesis is based mainly on binding studies in genital skin fibroblasts but the molecular evidence is sparse.
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|
pubmed:commentsCorrections |
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
0300-0664
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
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pubmed:volume |
54
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
827-34
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|
pubmed:dateRevised |
2006-11-15
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|
pubmed:meshHeading |
pubmed-meshheading:11422119-Animals,
pubmed-meshheading:11422119-Blotting, Western,
pubmed-meshheading:11422119-COS Cells,
pubmed-meshheading:11422119-Cells, Cultured,
pubmed-meshheading:11422119-Dihydrotestosterone,
pubmed-meshheading:11422119-Fibroblasts,
pubmed-meshheading:11422119-Follicle Stimulating Hormone,
pubmed-meshheading:11422119-Humans,
pubmed-meshheading:11422119-Infertility, Male,
pubmed-meshheading:11422119-Luteinizing Hormone,
pubmed-meshheading:11422119-Male,
pubmed-meshheading:11422119-Mutagenesis, Site-Directed,
pubmed-meshheading:11422119-Point Mutation,
pubmed-meshheading:11422119-Protein Binding,
pubmed-meshheading:11422119-Receptors, Androgen,
pubmed-meshheading:11422119-Sex Hormone-Binding Globulin,
pubmed-meshheading:11422119-Sperm Count,
pubmed-meshheading:11422119-Testosterone,
pubmed-meshheading:11422119-Transfection
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|
pubmed:year |
2001
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|
pubmed:articleTitle |
A novel mutation (N233K) in the transactivating domain and the N756S mutation in the ligand binding domain of the androgen receptor gene are associated with male infertility.
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|
pubmed:affiliation |
Department of Molecular Medicine, Karolinska Hospital, Stockholm, Sweden. ay.giwercman@swipnet.se
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
