Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2001-6-21
pubmed:abstractText
Genetically mediated taste responsiveness to 6-n-propylthiouracil (PROP) has been linked to reduced acceptance of some bitter foods. In this community-based study male (n = 364) and female (n = 378) adults enrolled in a self-help dietary intervention trial were screened for PROP taster status. Respondents, aged 18--70 years, were mailed filter papers impregnated with PROP or with aspartame solutions. They received instructions to rate taste intensity and hedonic preference using nine point category scales. Women rated PROP as more bitter than did men. Both sweetness and bitterness ratings were lower for older adults. Taste responsiveness to PROP was unrelated to body mass index in women or men. Higher bitterness ratings for PROP were weakly associated with higher sweetness ratings for aspartame, but were unrelated to sweet taste preferences. Successful administration of PROP filter papers by mail suggests new avenues for the screening of taste phenotypes in epidemiological studies.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0379-864X
pubmed:author
pubmed:issnType
Print
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
483-9
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed-meshheading:11418493-Adolescent, pubmed-meshheading:11418493-Adult, pubmed-meshheading:11418493-African Continental Ancestry Group, pubmed-meshheading:11418493-Age Factors, pubmed-meshheading:11418493-Aged, pubmed-meshheading:11418493-Asian Continental Ancestry Group, pubmed-meshheading:11418493-Aspartame, pubmed-meshheading:11418493-Body Mass Index, pubmed-meshheading:11418493-Data Collection, pubmed-meshheading:11418493-Epidemiologic Studies, pubmed-meshheading:11418493-European Continental Ancestry Group, pubmed-meshheading:11418493-Female, pubmed-meshheading:11418493-Food Habits, pubmed-meshheading:11418493-Humans, pubmed-meshheading:11418493-Male, pubmed-meshheading:11418493-Middle Aged, pubmed-meshheading:11418493-Phenotype, pubmed-meshheading:11418493-Propylthiouracil, pubmed-meshheading:11418493-Sex, pubmed-meshheading:11418493-Taste
pubmed:year
2001
pubmed:articleTitle
Genetic taste responses to 6-n-propylthiouracil among adults: a screening tool for epidemiological studies.
pubmed:affiliation
Nutritional Sciences Program and the Department of Epidemiology, University of Washington School of Public Health and Community Medicine, Seattle, WA 98195, USA. adamdrew@u.washington.edu
pubmed:publicationType
Journal Article, Clinical Trial, Randomized Controlled Trial, Controlled Clinical Trial