Linked Life Data

11417992

Source:http://linkedlifedata.com/resource/pubmed/id/11417992

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2001-6-21
pubmed:abstractText
Male breast cancer is a rare condition with very poorly understood risk factors. We report three cases of men with malignant and pre-malignant breast disease who had all been prescribed selective serotonin re-uptake inhibitors (SSRIs) for depression. Concerns about an association between this group of drugs and breast cancer in women have been previously raised and experimental evidence has suggested that these drugs could influence regulation of cellular proliferation acting through internal cellular messengers. Risk factors for the development of breast cancer are likely to be multifactorial, possibly more so in women given the complex physiological changes that occur in the female breast. Whilst the cases we report are anecdotal and other risk factors may be present, we suggest that assessment of any possible contribution that SSRI therapy may make to the development of breast neoplasia may be more easily assessed in a male population.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0748-7983
pubmed:author
pubmed:copyrightInfo
Copyright Harcourt Publishers Limited.
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
429-31
pubmed:dateRevised
2009-7-23
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Male breast neoplasia in association with selective serotonin re-uptake inhibitor therapy: a report of three cases.
pubmed:affiliation
Department of Histopathology, Northern General Hospital, Herries Road, Sheffield S5 7AU, UK. william.wallace@northngh-tr.trent.nhs.uk
pubmed:publicationType
Journal Article, Case Reports