Source:http://linkedlifedata.com/resource/pubmed/id/11412970
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
2001-6-19
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pubmed:abstractText |
A new support for solid-phase combinatorial organic synthesis has been developed, which we term a regio-reactive resin (R(3)-resin). The resin is based on a unique hydroxyl-functionalized cross-linker readily synthesized in two steps starting from 4-hydroxybenzaldehyde. The cross-linker's ease of synthesis and high purity enables the preparation of gel-type resins with regio-reactive orthogonal loading sites. The resin's swelling properties were investigated, and its potential utility was demonstrated via orthogonal reactivity of the pendant and cross-linker sites.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Alcohols,
http://linkedlifedata.com/resource/pubmed/chemical/Cross-Linking Reagents,
http://linkedlifedata.com/resource/pubmed/chemical/Polystyrenes,
http://linkedlifedata.com/resource/pubmed/chemical/Resins, Plant,
http://linkedlifedata.com/resource/pubmed/chemical/Water
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0960-894X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
18
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1507-9
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading | |
pubmed:year |
2001
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pubmed:articleTitle |
Regio-reactive resin: a platform for orthogonal loading using the polymer backbone and cross-linker.
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pubmed:affiliation |
Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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