Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2001-5-31
pubmed:abstractText
Previous studies demonstrated that dietary exposure to 24 ppb 3,3',4,4',5-pentachlorobiphenyl (PCB 126) or 2.4 ppb 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induced maxillary and mandibular proliferation of periodontal squamous epithelium, osteolysis of alveolar bone, and loose and displaced teeth in juvenile mink (Mustela vison). This study determined if such effects could be induced in laboratory rats. Feeding weanling male Long Evans rats 20 or 100 ppb PCB 126 or 1 or 10 ppb TCDD for up to 101 days caused a dose-dependent decrease in body weight gains but did not produce the jaw lesion observed in PCB 126- or TCDD-treated mink.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0145-6296
pubmed:author
pubmed:issnType
Print
pubmed:volume
43
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
170-1
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Dietary exposure to 3,3',4,4',5-pentachlorobiphenyl (PCB 126) or 2,3,7,8-tetrachlorodibenzo-p-dixon (TCDD) does not induce proliferation of squamous epithelium or osteolysis in the jaws of weanling rats.
pubmed:affiliation
Department of Animal Science and Institute for Environmental Toxicology, Michigan State University, East Lansing, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't