Linked Life Data

11377074

Source:http://linkedlifedata.com/resource/pubmed/id/11377074

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5-6
pubmed:dateCreated
2001-5-29
pubmed:abstractText
Three methods are described for the determination of lisinopril in the pharmaceutical tablets. The spectrophotometric method depends on the reaction of the lisinopril with sodium hypochlorite and phenyl hydrazine to form a condensation product measured at 362 nm. The spectrophotometric method was extended to develop a stability indicating method. The spectrofluorimetric method depends on reaction of the lisinopril with o-phthalaldehyde in the presence of 2-mercaptoethanol in borate buffer pH 9.5. The fluorescence of the reaction product was measured upon excitation at a maximum of 340 nm with emission wavelength at 455 nm. The HPLC method depends on using Hypersil silica column with a mobile phase consisting of methanol-water-triethylamine (50:50:0.1 v/v) and the pH was adjusted to 2.6 with 0.1 N perchloric acid. Quantitation was achieved with UV detection at 210 nm based on peak area.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0731-7085
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
913-22
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Spectrophotometric, septrofluorimetric and LC determination of lisinopril.
pubmed:affiliation
Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Suez Canal University, 41522, Ismailia, Egypt. ghada74@ismailia.ie-eg.com
pubmed:publicationType
Journal Article