pubmed-article:11376902 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:11376902 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
pubmed-article:11376902 | lifeskim:mentions | umls-concept:C0002395 | lld:lifeskim |
pubmed-article:11376902 | lifeskim:mentions | umls-concept:C1553372 | lld:lifeskim |
pubmed-article:11376902 | lifeskim:mentions | umls-concept:C2347026 | lld:lifeskim |
pubmed-article:11376902 | lifeskim:mentions | umls-concept:C0370003 | lld:lifeskim |
pubmed-article:11376902 | lifeskim:mentions | umls-concept:C0003595 | lld:lifeskim |
pubmed-article:11376902 | lifeskim:mentions | umls-concept:C1285573 | lld:lifeskim |
pubmed-article:11376902 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:11376902 | pubmed:dateCreated | 2001-5-29 | lld:pubmed |
pubmed-article:11376902 | pubmed:abstractText | Apolipoprotein E e4 (APOEe4) allele has been associated with an increased risk for Alzheimer's disease (AD) in diverse populations. Few studies have been carried out in Hispano-Americans and results are inconclusive due to ethnic diversity. This study determined the frequency of APOE alleles in a group of 61 Caucasian-Mestizos patients with probable AD, and 61 age- and sex-matched controls. APOEe4 frequency was 36.8% for patients, and 8.2% for controls (P < 0.0001; OR 7.6). Genotype frequencies differ between the two groups (P < 0.0001). Genotype 3/3 was the most common. Frequency of genotypes 3/4, 4/4 and 2/4 were higher in patients than in the controls. Our results show a highly significant association of APOEe4 with AD, and implies the importance of APOEe4 as a risk factor in this population. | lld:pubmed |
pubmed-article:11376902 | pubmed:language | eng | lld:pubmed |
pubmed-article:11376902 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11376902 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:11376902 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11376902 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11376902 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:11376902 | pubmed:month | Jun | lld:pubmed |
pubmed-article:11376902 | pubmed:issn | 0304-3940 | lld:pubmed |
pubmed-article:11376902 | pubmed:author | pubmed-author:YunisJ JJJ | lld:pubmed |
pubmed-article:11376902 | pubmed:author | pubmed-author:PardoRR | lld:pubmed |
pubmed-article:11376902 | pubmed:author | pubmed-author:GómezC MCM | lld:pubmed |
pubmed-article:11376902 | pubmed:author | pubmed-author:ArangoGG | lld:pubmed |
pubmed-article:11376902 | pubmed:author | pubmed-author:ArboledaHH | lld:pubmed |
pubmed-article:11376902 | pubmed:author | pubmed-author:ArboledaG HGH | lld:pubmed |
pubmed-article:11376902 | pubmed:author | pubmed-author:HedmontDD | lld:pubmed |
pubmed-article:11376902 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:11376902 | pubmed:day | 8 | lld:pubmed |
pubmed-article:11376902 | pubmed:volume | 305 | lld:pubmed |
pubmed-article:11376902 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:11376902 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:11376902 | pubmed:pagination | 135-8 | lld:pubmed |
pubmed-article:11376902 | pubmed:dateRevised | 2009-11-3 | lld:pubmed |
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pubmed-article:11376902 | pubmed:year | 2001 | lld:pubmed |
pubmed-article:11376902 | pubmed:articleTitle | Apolipoprotein E genotyping in a sample of Colombian patients with Alzheimer's disease. | lld:pubmed |
pubmed-article:11376902 | pubmed:affiliation | Genetics Institute, Faculty of Medicine, Universidad Nacional de Colombia, Bogota, Colombia. gonzalo.arboleda@stud.man.ac.uk | lld:pubmed |
pubmed-article:11376902 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:11376902 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
entrez-gene:348 | entrezgene:pubmed | pubmed-article:11376902 | lld:entrezgene |
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