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| pubmed-article:11374904 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:11374904 | pubmed:dateCreated | 2001-5-25 | lld:pubmed |
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| pubmed-article:11374904 | pubmed:abstractText | We describe the isolation and characterization of NSD3, the third member of a gene family including Nsd1 and NSD2. Murine Nsd1 was isolated in a search for proteins that interact with the ligand-binding domain of retinoic acid receptor alpha. NSD2 (also known as WHSC1 and MMSET) is located in the Wolf-Hirschhorn syndrome (WHS) critical region on 4p16.3 and is involved in multiple myeloma with t(4;14) translocations. The proteins Nsd1, NSD2, and NSD3 are highly similar within a block of about 700 amino acids. This block contains several conserved domains, such as the SET domain and the PHD finger, present in proteins involved in development and/or chromatin reorganization. The NSD3 gene consists of an 8.5-kb transcript composed of 23 coding exons and spans >90 kb of genomic DNA. NSD3 maps to chromosome band 8p12 and is amplified in several tumor cell lines and primary breast carcinomas. | lld:pubmed |
| pubmed-article:11374904 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:11374904 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:11374904 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11374904 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11374904 | pubmed:month | May | lld:pubmed |
| pubmed-article:11374904 | pubmed:issn | 0888-7543 | lld:pubmed |
| pubmed-article:11374904 | pubmed:author | pubmed-author:ChambonPP | lld:pubmed |
| pubmed-article:11374904 | pubmed:author | pubmed-author:StewartA FAF | lld:pubmed |
| pubmed-article:11374904 | pubmed:author | pubmed-author:DutrillauxBB | lld:pubmed |
| pubmed-article:11374904 | pubmed:author | pubmed-author:LossonRR | lld:pubmed |
| pubmed-article:11374904 | pubmed:author | pubmed-author:ApiouFF | lld:pubmed |
| pubmed-article:11374904 | pubmed:author | pubmed-author:AngrandP OPO | lld:pubmed |
| pubmed-article:11374904 | pubmed:copyrightInfo | Copyright 2001 Academic Press. | lld:pubmed |
| pubmed-article:11374904 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11374904 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:11374904 | pubmed:volume | 74 | lld:pubmed |
| pubmed-article:11374904 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11374904 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11374904 | pubmed:pagination | 79-88 | lld:pubmed |
| pubmed-article:11374904 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
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| pubmed-article:11374904 | pubmed:year | 2001 | lld:pubmed |
| pubmed-article:11374904 | pubmed:articleTitle | NSD3, a new SET domain-containing gene, maps to 8p12 and is amplified in human breast cancer cell lines. | lld:pubmed |
| pubmed-article:11374904 | pubmed:affiliation | Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Illkirch Cedex, C.U. de Strasbourg, F-67404, France. angrand@igbmc.u-strasbg.fr | lld:pubmed |
| pubmed-article:11374904 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11374904 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:11374904 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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