rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
2001-5-24
|
pubmed:abstractText |
We attempted to determine whether group IIA secretory phospholipase A2 (sPLA2-IIA) blockade after the onset of lung injury exerted therapeutic efficacy in the treatment of oleic acid (OA)-induced acute lung injury by using S-5920/LY315920Na, a novel specific inhibitor of sPLA2-IIA, with special interest in the changes of lung surfactant.
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0090-3493
|
pubmed:author |
pubmed-author:FurueSS,
pubmed-author:HoriYY,
pubmed-author:KuwabaraKK,
pubmed-author:MatsukawaAA,
pubmed-author:MikawaKK,
pubmed-author:NishinaKK,
pubmed-author:ObaraHH,
pubmed-author:OnoTT,
pubmed-author:ShigaMM,
pubmed-author:TeshirogiII,
pubmed-author:TomitaYY,
pubmed-author:UenoMM,
pubmed-author:YoshinagaMM
|
pubmed:issnType |
Print
|
pubmed:volume |
29
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
719-27
|
pubmed:dateRevised |
2009-6-23
|
pubmed:meshHeading |
pubmed-meshheading:11373455-Acetic Acids,
pubmed-meshheading:11373455-Animals,
pubmed-meshheading:11373455-Blood Gas Analysis,
pubmed-meshheading:11373455-Bronchoalveolar Lavage Fluid,
pubmed-meshheading:11373455-Enzyme Inhibitors,
pubmed-meshheading:11373455-Group II Phospholipases A2,
pubmed-meshheading:11373455-Indoles,
pubmed-meshheading:11373455-Male,
pubmed-meshheading:11373455-Oleic Acid,
pubmed-meshheading:11373455-Phospholipases A,
pubmed-meshheading:11373455-Phospholipases A2,
pubmed-meshheading:11373455-Pulmonary Surfactants,
pubmed-meshheading:11373455-Rabbits,
pubmed-meshheading:11373455-Respiratory Distress Syndrome, Adult
|
pubmed:year |
2001
|
pubmed:articleTitle |
Therapeutic time-window of a group IIA phospholipase A2 inhibitor in rabbit acute lung injury: correlation with lung surfactant protection.
|
pubmed:affiliation |
Discovery Research Laboratories, Shionogi & Co., Ltd., Osaka, Japan.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|